Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2017 Nov 2;43(1):98.
doi: 10.1186/s13052-017-0409-1.

Strategies for preventing group B streptococcal infections in newborns: a nation-wide survey of Italian policies

Collaborators, Affiliations
Comparative Study

Strategies for preventing group B streptococcal infections in newborns: a nation-wide survey of Italian policies

Chryssoula Tzialla et al. Ital J Pediatr. .

Abstract

Background: There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological practices for the GBS prevention.

Methods: Three distinct questionnaires were sent to obstetricians, neonatologists and microbiologists. Questionnaires included data on prenatal GBS screening, maternal risk factors, intrapartum antibiotic prophylaxis, microbiological information concerning specimen processing and GBS antimicrobial susceptibility.

Results: All respondent obstetrical units used the culture-based screening approach to identify women who should receive intrapartum antibiotic prophylaxis, and more than half of the microbiological laboratories (58%) reported using specimen processing consistent with CDC guidelines. Most neonatal units (89 out of 107, 82%) reported using protocols for preventing GBS early-onset sepsis consistent with CDC guidelines.

Conclusions: The screening-based strategy is largely prevalent in Italy, and most protocols for preventing GBS early-onset sepsis are consistent with CDC guidelines. However, we found discrepancies in practices among centers that may reflect the lack of Italian guidelines issued by public health organizations.

Keywords: GBS; Group B streptococcus; Infection; Neonate; Newborn infant; Survey.

PubMed Disclaimer

Conflict of interest statement

Ethics approval and consent to participate

Not applicable.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Comment in

References

    1. Stoll BJ, Hansen NI, Sánchez PJ, Faix RG, Poindexter BB, Van Meurs KP, et al., Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continues. Pediatrics. 2011; 127 (5):817–826. - PMC - PubMed
    1. Weston EJ, Pondo T, Lewis MM, Martell-Cleary P, Morin C, Jewell B, et al. The burden of invasive early-onset neonatal sepsis in the United States, 2005–2008. Pediatr Infect Dis J. 2011;30(11):937–941. doi: 10.1097/INF.0b013e318223bad2. - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention of perinatal group B streptococcal disease: a public health perspective. MMWR Recomm Rep 1996; 45:1–24. - PubMed
    1. Schrag S, Gorwitz R, Fulttz-Butts K, Schuchat A. Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC. MMWR Recomm Rep. 2002;51:1–22. - PubMed
    1. Verani JR, McGee L, Schrag SJ. Prevention of perinatal group B streptococcal disease- Revised guidelines from CDC, 2010. MMWR Recomm Rep. 2010;59:1–36. - PubMed

Publication types

MeSH terms