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Comment
. 2017 Dec;25(12):954-956.
doi: 10.1016/j.tim.2017.10.006. Epub 2017 Oct 30.

Anti-HIV Passive Immunization: New Weapons in the Arsenal

Ruth M Ruprecht  1
Affiliations
Comment

Anti-HIV Passive Immunization: New Weapons in the Arsenal

Ruth M Ruprecht. Trends Microbiol. 2017 Dec.

Abstract

Anti-HIV passive immunization with human neutralizing monoclonal antibodies (nmAbs) has made exciting gains: (i) identification of the HIV envelope V2 apex as a new in vivo protective epitope, (ii) a novel clade C SHIV for challenge studies, and (iii) a highly protective, trispecific nmAb. Potent, broad-spectrum protection by nmAbs holds promise.

Keywords: broadly neutralizing monoclonal antibody; clade C SHIV; nonhuman primate models; passive immunization; trispecific neutralizing monoclonal antibody.

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References

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