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Case Reports
. 2017 Nov-Dec;34(6):548-551.
doi: 10.4103/0970-2113.217574.

Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy

Gina Amanda  1 , Agus Dwi Susanto  1 , Dicky Soehardiman  1 , Dianiati Kusumo Sutoyo  1 , Yuyun Lisnawati  2 , Boy Busmar  2 , Andika Chandra Putra  1 , Erlang Samoedro  1 , Elisna Syahruddin  1
Affiliations
Case Reports

Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy

Gina Amanda et al. Lung India. 2017 Nov-Dec.

Abstract

Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Chest X-ray: Nonhomogeneous consolidation in the left hemithorax with pleural effusion. No mediastinal deviation after inserting water-sealed drainage catheter
Figure 2
Figure 2
Computed tomography of the thorax with contrast: (Left) a mass lesion in the left hemithorax, extending to the chest wall and mediastinum with bilateral pleural effusion and left pleural thickening. (Right) multiple metastatic nodules in the liver
See this image and copyright information in PMC

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