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Case Reports
. 1989 Jan;39(1):140-1.
doi: 10.1212/wnl.39.1.140.

Monozygotic twins concordant for the narcoleptic syndrome

A B Douglass  1 , L Harris, F Pazderka
Affiliations
Case Reports

Monozygotic twins concordant for the narcoleptic syndrome

A B Douglass et al. Neurology. 1989 Jan.

Abstract

We report the first documented monozygotic twins who both had the narcoleptic syndrome. We assessed monozygosity by HLA antigens and by blood groups. In contrast to virtually all other narcoleptics, they had HLA-DQ1 instead of HLA-DR2; this helped to localize the gene, and perhaps explains its greater expressivity in these than in other twins.

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Comment in

  • Narcoleptic twins.
    Carlson SE. Carlson SE. Neurology. 1989 Jul;39(7):1005-6. doi: 10.1212/wnl.39.7.1005-a. Neurology. 1989. PMID: 2787004 No abstract available.

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