Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Nov 2;21(5):566-568.
doi: 10.1016/j.stem.2017.10.006.

EMPhasis on Mutant Microglia: Dysregulation of Brain Sentinels Induces Neurodegeneration

Bettina Schreiner  1 , Melanie Greter  2
Affiliations
Free article
Comment

EMPhasis on Mutant Microglia: Dysregulation of Brain Sentinels Induces Neurodegeneration

Bettina Schreiner et al. Cell Stem Cell. .
Free article

Abstract

Reactive microglia are often implicated in the pathology of neurodegenerative disease. In a recent study in Nature, Mass et al. (2017) demonstrate that targeted mutation of Braf in early erythro-myeloid precursors (EMPs) causes histiocytosis-associated late onset neurodegeneration driven by activated microglia.

PubMed Disclaimer

Comment on

LinkOut - more resources