Can U Turn ILC2s Up?
- PMID: 29100072
- DOI: 10.1016/j.cell.2017.10.013
Can U Turn ILC2s Up?
Abstract
Innate lymphoid cells (ILCs) are tuned to quickly respond to and amplify tissue-specific signals. Work of three independent groups in Nature uncovers a novel mode of inflammatory communication between ILC2s and neurons at mucosal surfaces.
Copyright © 2017. Published by Elsevier Inc.
Comment on
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The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.Nature. 2017 Sep 14;549(7671):282-286. doi: 10.1038/nature23676. Epub 2017 Sep 6. Nature. 2017. PMID: 28869965 Free PMC article.
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Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.Nature. 2017 Sep 14;549(7671):277-281. doi: 10.1038/nature23469. Epub 2017 Sep 6. Nature. 2017. PMID: 28869974 Free PMC article.
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The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.Nature. 2017 Sep 21;549(7672):351-356. doi: 10.1038/nature24029. Epub 2017 Sep 13. Nature. 2017. PMID: 28902842 Free PMC article.
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