The yin and yang of cytokine priming on the macrophage epigenome
- PMID: 29101211
- DOI: 10.1126/sciimmunol.aaq0016
The yin and yang of cytokine priming on the macrophage epigenome
Abstract
TNF and type I interferons alter TLR4 responses by reprogramming the macrophage genome.
Copyright © 2017, American Association for the Advancement of Science.
Comment on
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Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation.Nat Immunol. 2017 Oct;18(10):1104-1116. doi: 10.1038/ni.3818. Epub 2017 Aug 21. Nat Immunol. 2017. PMID: 28825701 Free PMC article.
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