Multiple increase in productivity of the yeast at reducing the fraction of D2O in water

Abstract

We found a two-fold increase in the productivity of baker's yeast grown on a nutrient mixture prepared in light water with a D₂O content (127 ppm) smaller than in the distilled water (150 ppm). The number of water monomers that provides the biosynthetic activity (water transport through membrane channels) of yeast cells with an increased CO₂ yield was determined for the first time. We established that the selectivity of cell membrane channels in water of different composition depends not only on the motion of ortho-and para-spin H₂O isomers in solution, as was shown earlier, but also on the concentration of D₂O.