Acquiring new N-glycosylation sites in variable regions of immunoglobulin genes by somatic hypermutation is a common feature of autoimmune diseases
- PMID: 29102958
- DOI: 10.1136/annrheumdis-2017-212568
Acquiring new N-glycosylation sites in variable regions of immunoglobulin genes by somatic hypermutation is a common feature of autoimmune diseases
Keywords: B cells; Sjøgren’s syndrome; autoimmune diseases; rheumatoid arthritis.
Conflict of interest statement
Competing interests: None declared.
Comment in
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Response to: 'Acquiring new N-glycosylation sites in variable regions of immunoglobulin genes by somatic hypermutation is a common feature of autoimmune diseases' by Visser et al.Ann Rheum Dis. 2018 Oct;77(10):e70. doi: 10.1136/annrheumdis-2017-212583. Epub 2017 Nov 23. Ann Rheum Dis. 2018. PMID: 29170200 No abstract available.
Comment on
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B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation.Ann Rheum Dis. 2018 Jun;77(6):956-958. doi: 10.1136/annrheumdis-2017-212052. Epub 2017 Aug 23. Ann Rheum Dis. 2018. PMID: 28835463 No abstract available.
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