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Case Reports
. 2018 Nov;24(13):1770-1772.
doi: 10.1177/1352458517739990. Epub 2017 Nov 6.

The NAIMS cooperative pilot project: Design, implementation and future directions

Jiwon Oh  1 , Rohit Bakshi  2 , Peter A Calabresi  3 , Ciprian Crainiceanu  3 , Roland G Henry  4 , Govind Nair  5 , Nico Papinutto  4 , R Todd Constable  6 , Daniel S Reich  5 , Daniel Pelletier  7 , William Rooney  8 , Daniel Schwartz  8 , Ian Tagge  8 , Russell T Shinohara  9 , Jack H Simon  8 , Nancy L Sicotte  10 ; NAIMS Cooperative Steering Committee
Affiliations
Case Reports

The NAIMS cooperative pilot project: Design, implementation and future directions

Jiwon Oh et al. Mult Scler. 2018 Nov.

Abstract

The North American Imaging in Multiple Sclerosis (NAIMS) Cooperative represents a network of 27 academic centers focused on accelerating the pace of magnetic resonance imaging (MRI) research in multiple sclerosis (MS) through idea exchange and collaboration. Recently, NAIMS completed its first project evaluating the feasibility of implementation and reproducibility of quantitative MRI measures derived from scanning a single MS patient using a high-resolution 3T protocol at seven sites. The results showed the feasibility of utilizing advanced quantitative MRI measures in multicenter studies and demonstrated the importance of careful standardization of scanning protocols, central image processing, and strategies to account for inter-site variability.

Keywords: MRI; North America; collaboration.

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Figures

Figure 1
Figure 1. Sagittal FLAIR Sequence Acquired in Single MS Subject Across NAIMS Sites (manually-segmented T2-lesion volumes are presented beside each center name)
A: Harvard University (19.1 mL); B: Cedars-Sinai Medical Center (17.2 mL); C: Johns Hopkins University (16.5 mL); D: National Institutes of Health (17.9 mL); E: Oregon Health and Science University (16.3 mL); F: University of California at San Francisco (19.3 mL); G: Yale University (19.4 mL)
See this image and copyright information in PMC

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