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. 2018 Mar;98(3):300-304.
doi: 10.1016/j.jhin.2017.10.015. Epub 2017 Oct 26.

Clonal spread of carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit

W G Maciel  1 , K E da Silva  1 , J Croda  2 , R Cayô  3 , A C Ramos  3 , R O de Sales  1 , G H de Almeida de Souza  1 , J V B Bampi  1 , L C Limiere  4 , J C Casagrande  4 , A C Gales  3 , S Simionatto  5
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Clonal spread of carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit

W G Maciel et al. J Hosp Infect. 2018 Mar.

Abstract

Acinetobacter baumannii has often been associated with colonization and/or infection in neonatal intensive care units (NICU). This study describes a clonal spread of carbapenem-resistant A. baumannii (CRAB) isolates in an NICU. In total, 21 CRAB isolates were collected from premature newborns. Only polymyxin B was active against such isolates. Nineteen CRAB isolates were clonally related (Cluster C, which belonged to worldwide-disseminated ST1). All newborns had peripheral access and had received β-lactam therapy previously. The implementation of strict infection control measures was of fundamental importance to eradicate the clonal type in the study hospital.

Keywords: Carbapenem; Colonization; Multi-drug-resistant; NICU.

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