Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Dec 1;82(11):e81-e83.
doi: 10.1016/j.biopsych.2017.09.025.

Metabolism and Memory: Obesity, Diabetes, and Dementia

Daniel Shalev  1 , Melissa R Arbuckle  2
Affiliations
Comment

Metabolism and Memory: Obesity, Diabetes, and Dementia

Daniel Shalev et al. Biol Psychiatry. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Disclosures

The authors report no biomedical financial interests or potential conflicts of interest.

Figures

Figure 1
Figure 1
Metabolic and inflammatory mediators released by adipose tissue and the pancreas impact the brain in both health and disease. Diabetes and obesity may contribute to dementia via these mediators. CNS, central nervous system.
See this image and copyright information in PMC

Comment on

References

    1. Ogden CL, Carroll MD, Kit BK, Flegal KM. [Accessed September 21, 2017];Prevalence of obesity in the United States, 2009–2010. 2012 Available at: https://www.cdc.gov/nchs/data/databriefs/db82.pdf. - PubMed
    1. Pedditizi E, Peters R, Beckett N. The risk of overweight/obesity in mid-life and late life for the development of dementia: A systematic review and meta-analysis of longitudinal studies. Age Ageing. 2016;45:14–21. - PubMed
    1. Zhang J, Chen C, Hua S, Liao H, Wang M, Xiong Y, Cao F. An updated meta-analysis of cohort studies: Diabetes and risk of Alzheimer’s disease. Diabetes Res Clin Pract. 2017;124:41–47. - PubMed
    1. Walker JM, Harrison FE. Shared neuropathological characteristics of obesity, type 2 diabetes and Alzheimer’s disease: Impacts on cognitive decline. Nutrients. 2015;7:7332–7357. - PMC - PubMed
    1. Kiliaan AJ, Arnoldussen IAC, Gustafson DR. Adipokines: A link between obesity and dementia? Lancet Neurol. 2014;13:913–923. - PMC - PubMed

Publication types

Substances