Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2018 Jul-Aug;20(4):405-406.
doi: 10.4103/aja.aja_38_17.

Hormone levels following surgical and medical castration: defining optimal androgen suppression

Michael T Schweizer  1   2 , Michael L Hancock  3 , Robert H Getzenberg  4 , Evan Y Yu  1   2
Affiliations
Randomized Controlled Trial

Hormone levels following surgical and medical castration: defining optimal androgen suppression

Michael T Schweizer et al. Asian J Androl. 2018 Jul-Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

MLH and RHG are former employees of GTx, Inc, the sponsor of the clinical trial from which these data were derived. MTS and EYY have no competing interests to declare

References

    1. Nishiyama T. Serum testosterone levels after medical or surgical androgen deprivation: a comprehensive review of the literature. Urol Oncol. 2014;32:38e17–28. - PubMed
    1. Klotz L, O'Callaghan C, Ding K, Toren P, Dearnaley D, et al. Nadir testosterone within first year of androgen-deprivation therapy (ADT) predicts for time to castration-resistant progression: a secondary analysis of the PR-7 trial of intermittent versus continuous ADT. J Clin Oncol. 2015;33:1151–6. - PMC - PubMed
    1. Mendel CM. The free hormone hypothesis: a physiologically based mathematical model. Endocr Rev. 1989;10:232–74. - PubMed
    1. Smith MR, Morton RA, Barnette KG, Sieber PR, Malkowicz SB, et al. Toremifene to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer. J Urol. 2013;189:S45–50. - PubMed
    1. Winters SJ, Kelley DE, Goodpaster B. The analog free testosterone assay: are the results in men clinically useful? Clin Chem. 1998;44:2178–82. - PubMed