Spread through air spaces (STAS): a comprehensive update
- PMID: 29114466
- PMCID: PMC5653519
- DOI: 10.21037/tlcr.2017.06.08
Spread through air spaces (STAS): a comprehensive update
Abstract
The new concept of spread through air spaces (STAS) was introduced for pulmonary adenocarcinomas (ADC) in the 2015 World Health Organization (WHO) classification for lung cancer. Yet available data demonstrate that STAS is of high prognostic impact and associated with specific clinic-pathological characteristics. This article provides a comprehensive overview on recent developments in this field.
Keywords: Spread through air spaces (STAS); lung cancer; metastasis; prognosis; recurrence.
Conflict of interest statement
Conflicts of Interest: The author has no conflicts of interest to declare.
References
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- Kadota K, Nitadori J, Sima CS, et al. Tumor Spread through Air Spaces is an Important Pattern of Invasion and Impacts the Frequency and Location of Recurrences after Limited Resection for Small Stage I Lung Adenocarcinomas. J Thorac Oncol 2015;10:806-14. 10.1097/JTO.0000000000000486 - DOI - PMC - PubMed
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