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Review
. 2018 Mar;61(3):309-325.
doi: 10.1002/jlcr.3581. Epub 2018 Jan 5.

Radiopharmaceuticals for imaging and endoradiotherapy of neurotensin receptor-positive tumors

Simone Maschauer  1 , Olaf Prante  1
Affiliations
Review

Radiopharmaceuticals for imaging and endoradiotherapy of neurotensin receptor-positive tumors

Simone Maschauer et al. J Labelled Comp Radiopharm. 2018 Mar.

Abstract

The neurotensin receptors are overexpressed in various tumor types, especially in highly progressive pancreatic tumors. As this cancer has a poor 5-year survival prognosis, there is an urgent need to improve early diagnosis and treatment strategies. This review article provides an overview of the latest developments in radiopharmaceuticals for neurotensin receptor-positive tumors, including peptidic and non-peptidic radiopharmaceuticals, not only for SPECT and PET but also for endoradiotherapy.

Keywords: NTS1; PET; SPECT; endoradiotherapy; neurotensin; neurotensin receptor; pancreatic tumor.

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