Comparative Study
Three-dimensional structures of proteins in solution by nuclear magnetic resonance spectroscopy
Affiliations
- PMID: 2911557
Item in Clipboard
Comparative Study
Three-dimensional structures of proteins in solution by nuclear magnetic resonance spectroscopy
Protein Seq Data Anal.
1989.
Abstract
Nuclear magnetic resonance (NMR) spectroscopy has emerged in recent years as a powerful method for the determination of three dimensional structures of small proteins in solution. Major cornerstones towards these advances were the introduction of two dimensional NMR experiments in combination with high field superconducting magnets, as well as the development of computational procedures to convert NMR derived distances into a 3D structure. This article outlines the methodology employed and illustrates its applicability based on a variety of examples.
Similar articles
-
Determination of three-dimensional structures of proteins and nucleic acids in solution by nuclear magnetic resonance spectroscopy.Crit Rev Biochem Mol Biol. 1989;24(5):479-564. doi: 10.3109/10409238909086962. Crit Rev Biochem Mol Biol. 1989. PMID: 2676353 Review.
-
Three-dimensional NMR spectroscopy of a protein in solution.Nature. 1988 Mar 24;332(6162):374-6. doi: 10.1038/332374a0. Nature. 1988. PMID: 3352736
-
Nuclear magnetic resonance-based modeling and refinement of protein three-dimensional structures and their complexes.Methods Mol Biol. 2008;443:229-55. doi: 10.1007/978-1-59745-177-2_13. Methods Mol Biol. 2008. PMID: 18446291
-
Structures of protein complexes by multidimensional heteronuclear magnetic resonance spectroscopy.Crit Rev Biochem Mol Biol. 1995;30(5):351-85. doi: 10.3109/10409239509083489. Crit Rev Biochem Mol Biol. 1995. PMID: 8575189 Review.
-
Advances of high-resolution NMR techniques in the structural and metabolic analysis of plant biochemistry.Phytochemistry. 2007 Nov-Dec;68(22-24):2799-815. doi: 10.1016/j.phytochem.2007.09.028. Epub 2007 Nov 19. Phytochemistry. 2007. PMID: 18023829 Review.