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Comment
. 2017 Nov 7;26(5):699-700.
doi: 10.1016/j.cmet.2017.10.014.

NFIL-trating the Host Circadian Rhythm-Microbes Fine-Tune the Epithelial Clock

Christoph A Thaiss  1 , Samuel P Nobs  1 , Eran Elinav  2
Affiliations
Comment

NFIL-trating the Host Circadian Rhythm-Microbes Fine-Tune the Epithelial Clock

Christoph A Thaiss et al. Cell Metab. .

Abstract

The diurnal activities of the intestinal microbiota and its host are closely connected, but the nature of their circadian communication pathways remains obscure. Wang et al. (2017) have described a signaling circuit linking microbial sensing by the immune system to the epithelial clock, thereby orchestrating local and systemic lipid metabolism.

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