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Case Reports
. 2017 Oct;10(5):325-327.
doi: 10.14740/gr878w. Epub 2017 Oct 26.

Eosinophilic Colitis Masquerading as Malignancy of Colon

Tagore Sunkara  1 , Arash Samarghandi  2 , Sriharsha Dadana  2 , Vinaya Gaduputi  2
Affiliations
Case Reports

Eosinophilic Colitis Masquerading as Malignancy of Colon

Tagore Sunkara et al. Gastroenterology Res. 2017 Oct.

Abstract

Eosinophilic colitis (EC) is a rare part of spectrum of diseases called eosinophilic gastrointestinal disease (EGID). It was found to have bimodal distribution involving neonates and adults in age groups of 30 - 50 with male preponderance. We present this case of a 78-year-old woman who came to the hospital with abdominal pain, hematochezia and unintentional weight loss, and was found to have EC. This case was very unique given the age at presentation and the radiological findings mimicking malignancy. We reviewed the possible etiologies, clinical features, pathology, and treatment of EC along with the review of the literature.

Keywords: Colon malignancy; Eosinophilic colitis; Eosinophilic gastroenteritis; Eosinophilic gastrointestinal disease.

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Figures

Figure 1
Figure 1
Computerized tomography (CT) scan of the abdomen/pelvis showing focal circumferential mass like thickening in colon with paracolic infiltration (arrow).
Figure 2
Figure 2
Colonoscopy showing circumferential, ulcerated and friable mucosa.
Figure 3
Figure 3
Biopsies showed friable mucosa with ulcerations (not pictured) and numerous eosinophils within the deep portions of lamina propria, muscularis mucosae, and submucosa.
See this image and copyright information in PMC

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