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Review
. 2017 Oct 25:7:449.
doi: 10.3389/fcimb.2017.00449. eCollection 2017.

Neurological Manifestations of Dengue Infection

Guo-Hong Li  1 , Zhi-Jie Ning  2 , Yi-Ming Liu  3 , Xiao-Hong Li  1
Affiliations
Review

Neurological Manifestations of Dengue Infection

Guo-Hong Li et al. Front Cell Infect Microbiol. .

Abstract

Dengue counts among the most commonly encountered arboviral diseases, representing the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each year >2.5 billion people are at risk of dengue virus infection worldwide. Neurological signs of dengue infection are increasingly reported. In this review, the main neurological complications of dengue virus infection, such as central nervous system (CNS), peripheral nervous system, and ophthalmic complications were discussed according to clinical features, treatment and possible pathogenesis. In addition, neurological complications in children were assessed due to their atypical clinical features. Finally, dengue infection and Japanese encephalitis were compared for pathogenesis and main clinical manifestations.

Keywords: dengue; in children; manifestations; neurological complications; neuropathogenesis; prevention; treatment.

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