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. 2017 Nov;164(1):106-108.
doi: 10.1007/s10517-017-3935-3. Epub 2017 Nov 9.

Potentialities of MicroRNA Diagnosis in Patients with Bladder Cancer

P V Shegay  1 , A A Zhavoronkov  2 , N M Gaifullin  3 , N V Vorob'ev  4 , B Ya Alekseev  4 , S V Popov  4 , A V Garazha  2 , A A Buzdin  2 , A D Kaprin  4
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Potentialities of MicroRNA Diagnosis in Patients with Bladder Cancer

P V Shegay et al. Bull Exp Biol Med. 2017 Nov.

Abstract

Despite promising vista of the use of microRNA in molecular diagnosis of bladder cancer, there are few data on their expression profiles, which impedes assessment of diagnostic value of these marker molecules. In this study, suppression subtractive hybridization, on-chip hybridization, and high-throughput deep sequencing focused on profiling microRNA and assessing the diagnostic value of revealed marker molecules.

Keywords: cancer; deep sequencing; diagnostics; microRNA; urinary bladder.

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