Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: communication from the SSC of the ISTH

A Iorio^{1

2}, V Blanchette³, J Blatny⁴, P Collins⁵, K Fischer⁶, E Neufeld⁷

Affiliations

¹ Department of Health Research, Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
² Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
³ Division of Hematology/Oncology, Hospital for Sick Children and Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
⁴ Department of Pediatric Hematology, University Hospital Brno, Brno, Czech Republic.
⁵ Arthur Bloom Haemophilia Centre, School of Medicine, University Hospital of Wales, Cardiff University, Cardiff, UK.
⁶ Van Creveldkliniek, University Medical Center, Utrecht, the Netherlands.
⁷ St Jude Children's Research Hospital, Memphis, TN, USA.

Free article

Practice Guideline

A Iorio et al. J Thromb Haemost. 2017 Dec.

Free article

. 2017 Dec;15(12):2461-2465.

doi: 10.1111/jth.13867. Epub 2017 Nov 9.

A Iorio^{1

2}, V Blanchette³, J Blatny⁴, P Collins⁵, K Fischer⁶, E Neufeld⁷

¹ Department of Health Research, Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
² Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
³ Division of Hematology/Oncology, Hospital for Sick Children and Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
⁴ Department of Pediatric Hematology, University Hospital Brno, Brno, Czech Republic.
⁵ Arthur Bloom Haemophilia Centre, School of Medicine, University Hospital of Wales, Cardiff University, Cardiff, UK.
⁶ Van Creveldkliniek, University Medical Center, Utrecht, the Netherlands.
⁷ St Jude Children's Research Hospital, Memphis, TN, USA.

No abstract available

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