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. 2017;12(3):192-198.
doi: 10.5114/pg.2017.70472. Epub 2017 Sep 30.

The impact of age and sex on the occurrence of pathology in the wall of the upper gastrointestinal tract

Przemysław Dyrla  1 , Jerzy Gil  1 , Stanisław Niemczyk  2 , Marek Saracyn  3 , Krzysztof Kosik  1 , Sebastian Czarkowski  4 , Arkadiusz Lubas  2
Affiliations

The impact of age and sex on the occurrence of pathology in the wall of the upper gastrointestinal tract

Przemysław Dyrla et al. Prz Gastroenterol. 2017.

Abstract

Introduction: The growing incidence of gastrointestinal diseases forces to improve both imaging techniques and the identification of the population with a greater risk of a disease. Identification of lesions located inside the wall of intestinal tract or in close proximity often was not possible using endoscopy or computed tomography.

Aim: The study was a retrospective evaluation of the occurrence of submucosal lesions (SML) and thickened wall (TW) of the upper gastrointestinal tract (UGIT) depending on age and sex.

Material and methods: Out of 20012 gastroscopies during the 4-year follow-up study, we enrolled 199 patients with pathological lesions in the wall of the UGIT. All patients underwent computed tomography and endoscopic ultrasound (EUS).

Results: We analysed a total of 122 (78 males, 44 females, age: 64.0 ±12.9 years) out of 187 patients. 23.91% of SML in the oesophagus, 56.52% in the stomach, and 19.57% in the duodenum. A higher number of SMLs was found in men than in women (57.14% vs. 40.45%, p = 0.023), and the difference was greater over 50 years of age (85.71% vs. 40.00%, p = 0.031). We found less malignant SMLs compared to benign (35.87% vs. 64.13%, p = 0.026), especially in women (22.86% vs. 47.46%, p = 0.006). 26.67% of TW were in the oesophagus, 66.67% in the stomach, and 6.67% in the duodenum. There was a tendency towards increased incidence of TW over 50 years of age (8.58% vs. 18.30%, p = 0.074), which concerned men in particular (24.10% vs. 11.43%, p = 0.043). Until 65 years of age, these differences were significant for the oesophagus (27.27% vs. 0.00%, p = 0.044) and the stomach (25.93% vs. 4.00%, p = 0.029). As many as 70% of TW pathologies were malignant.

Conclusions: Submucosal lesions and TW of the upper gastrointestinal tract account for 0.61% of performed gastroscopies. They occur in men and usually over 50 years of age.

Keywords: endosonography; gastroscopy; submucosal lesions; thickened wall.

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References

    1. Dietrich CF. Endoscopic Ultrasound. 2nd ed. Stuttgart: Thieme; 2011. pp. 224–77.
    1. Dyrla P, Gil J, Wojtuń S, et al. Pancreatic pseudocyst in the mediastinum. Pol Arch Med Wewn. 2014;124:270–1. - PubMed
    1. Lewosiuk A, Białek A, Smereczyński A, et al. Submucosal tumors of upper gastrointestinal tract. Prz Gastroenterol. 2009;4:126–36.
    1. Xu GQ, Qian JJ, Chen MH, et al. Endoscopic ultrasonography for the diagnosis and selecting treatment of esophageal leiomyoma. J Gastroenterol Hepatol. 2011;14:1440–6. - PubMed
    1. Tae HJ, Lee HL, Lee KN, et al. Deep biopsy via endoscopic submucosal dissection in upper gastrointestinal subepithelial tumors: a prospective study. Endoscopy. 2014;46:845–50. - PubMed