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Case Reports
. 2016 May 16;4(1):93-96.
doi: 10.1002/ams2.220. eCollection 2017 Jan.

Post-traumatic hypopituitarism: report of a child case

Affiliations
Case Reports

Post-traumatic hypopituitarism: report of a child case

Makoto Aoki et al. Acute Med Surg. .

Abstract

Case: We report a case of post-traumatic hypopituitarism in a 9-year-old boy who was injured in a car accident.

Outcome: Post-traumatic hypopituitarism might be caused by moderate to severe head trauma, and while this possibility has recently drawn attention in adults, few reports are available regarding children. Our patient experienced head and facial injury, resulting in post-traumatic hypopituitarism. Six hours after injury he suffered from diabetes insipidus and hormone replacement therapy was started. On day 12 he underwent facial fracture reduction under general anesthesia. On day 24 he was discharged from the hospital. One year after the injury, secretory function and water dehydration tests suggested the possibility of post-traumatic hypopituitarism.

Conclusion: We experienced a child case of post-traumatic hypopituitarism. Emergency physicians should pay attention to the possibility of post-traumatic hypopituitarism in cases of traumatic brain injury.

Keywords: Child; diabetes insipidus; head trauma; hypopituitarism.

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Figures

Figure 1
Figure 1
Computed tomography of a 9‐year‐old boy who was injured in a car accident, carried out on arrival at hospital. A, Pneumocephalus inside the frontal cranial bone (arrow). B, Fracture of the frontal cranial bone (arrow).
Figure 2
Figure 2
Head magnetic resonance imaging of a 9‐year‐old boy who was injured in a car accident. The T1‐weighted image shows the normal appearance of a high intensity signal in the posterior pituitary lobe (arrow).

References

    1. Schneider HJ, Corneli G, Kreitschman‐Andermahr I et al Traumatic brain injury and hypopituitarism in children and adolescents: is the problem under‐estimated? Pediatr. Endocrinol. Rev. 2007; 4: 205–9. - PubMed
    1. Agha A, Phillips J, Thompson CJ. Hypopituitarism following traumatic brain injury (TBI). Br. J. Neurosurg. 2007; 21: 210–6. - PubMed
    1. Leal‐Cerro A, Flores JM, Rincon M et al Prevalence of hypopituitarism and growth hormone deficiency in adults long‐term after severe traumatic brain injury. Clin. Endocrinol. (Oxf). 2005; 62: 525–32. - PubMed
    1. Girard J, Marelli R. Posttraumatic hypothalamo‐pituitary insufficiency. Diagnostic and therapeutic problems in a prepubertal child. J. Pediatr. 1997; 90: 241–2. - PubMed
    1. Khadr SN, Crofton PM, Jones PA et al Evaluation of pituitary function after traumatic brain injury in childhood. Clin. Endocrinol. (Oxf). 2010; 73: 637–43. - PubMed

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