Impact of Ultraviolet Light on Vitiligo

Abstract

Vitiligo is a disorder of the melanocytes that results in a dynamic spectrum of skin depigmentation. Its etiology is complex and multifactorial, with data supporting several different hypotheses. Given its prominent phenotype, vitiligo has a significant negative impact on quality of life. Coupled with the chronic and incurable nature of the disease, this presents a formidable treatment challenge. Several treatment modalities have been instituted over the years, with varying efficacy. This chapter focuses on the use of ultraviolet light in vitiligo as an established therapeutic option.

Keywords: Inflammatory; Light; Narrowband; PUVA; Phototherapy; Repigmentation; UVB; Ultraviolet; VASI; Vitiligo.