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Comment
. 2018 Mar;32(3):483-486.
doi: 10.1038/eye.2017.220. Epub 2017 Nov 10.

Role of pericytes in the retina

G S P Santos  1 , P H D M Prazeres  1 , A Mintz  2 , A Birbrair  1
Affiliations
Comment

Role of pericytes in the retina

G S P Santos et al. Eye (Lond). 2018 Mar.
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Retinal vasculature in diabetic retinopathy. Pericytes are present around blood vessels in the normal retina. Pericyte dropout is one of the major hallmarks of diabetic retinopathy. Park and colleagues now suggest that pericytes are essential in the formation and maturation of blood-retinal-barrier at the postnatal stage through active recruitment of pericytes onto the growing retinal vessels. Nevertheless, pericytes are not indispensable in the adult stable retinal blood vessels; and their selective depletion did not lead to a phenotype similar to diabetic retinopathy. Future studies may reveal other role of retinal pericytes in much greater detail.
See this image and copyright information in PMC

Comment on

  • Plastic roles of pericytes in the blood-retinal barrier.
    Park DY, Lee J, Kim J, Kim K, Hong S, Han S, Kubota Y, Augustin HG, Ding L, Kim JW, Kim H, He Y, Adams RH, Koh GY. Park DY, et al. Nat Commun. 2017 May 16;8:15296. doi: 10.1038/ncomms15296. Nat Commun. 2017. PMID: 28508859 Free PMC article.

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