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Review
. 2017 Dec;38(4):751-759.
doi: 10.1016/j.ccm.2017.07.007. Epub 2017 Aug 31.

Evaluation and Management of the Potential Lung Donor

Andrew Courtwright  1 , Edward Cantu  2
Affiliations
Review

Evaluation and Management of the Potential Lung Donor

Andrew Courtwright et al. Clin Chest Med. 2017 Dec.

Abstract

The expansion of the donor lung pool has involved an evidence-driven redefinition of acceptable donors. Proceeding with transplantation with an acceptable rather than ideal donor depends on specific patient-related and organ-related risk factors as well as the severity of recipient illness. Although the physiologic optimization of brain-dead donors has not changed significantly in recent years, the use of donor management protocols has improved procurement rates. Ex vivo lung perfusion is an increasingly viable strategy to recondition lungs that would otherwise fall below the acceptable threshold for transplant. Ex vivo perfusion trials for preservation of standard donor lungs are ongoing.

Keywords: Brain death; Donor lung management; EVLP; Ex vivo perfusion; Lung transplant; Organ donor.

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References

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