Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Jan;21(1):36-44.
doi: 10.1111/1756-185X.13224. Epub 2017 Nov 13.

Diagnosis of Kawasaki disease

Affiliations
Review

Diagnosis of Kawasaki disease

Surjit Singh et al. Int J Rheum Dis. 2018 Jan.

Abstract

Kawasaki disease (KD) is a medium vessel vasculitis with predilection for coronary arteries. Due to lack of a reliable confirmatory laboratory test, the diagnosis of KD is based on a constellation of clinical findings that appear in a typical temporal sequence. These diagnostic criteria have been modified from time to time and the most recent guidelines have been proposed by the American Heart Association (AHA) in 2017. However, several children may have incomplete or atypical forms of KD and the diagnosis can often be difficult, especially in infants and young children. In this review, we have detailed the steps involved in arriving at a diagnosis of KD and also highlight the important role of echocardiography in diagnosis and management of children with KD.

Keywords: AHA; Kawasaki disease; diagnosis; echocardiography.

PubMed Disclaimer

Conflict of interest statement

None.

References

    1. Newburger JW, Takahashi M, Gerber MA, et al (2004) Diagnosis, treatment, and long‐term management of Kawasaki disease: a statement for health professionals from the committee on Rheumatic fever, Endocarditis and Kawasaki disease, council on Cardiovascular disease in the young. American Heart Association. Circulation 110, 2747–71. - PubMed
    1. Kawasaki T (1967) Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi Allergy 16, 178–222. - PubMed
    1. Ayusawa M, Sonobe T, Uemura S, et al (2005) Revision of diagnostic guidelines for Kawasaki disease (the 5th revised edition). Pediatr Int 47 (2), 232–4. - PubMed
    1. McCrindle BW, Rowley AH, Newburger JW, et al (2017) Diagnosis, treatment, and long‐term management of Kawasaki disease: a scientific statement for health professionals from the American heart association. Circulation 135, e927–99. - PubMed
    1. Yoshino A, Tanaka R, Takano T, Oishi T (2017) Afebrile Kawasaki disease with coronary artery dilatation. Pediatr Int 59, 375–7. - PubMed

MeSH terms