Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2018 Jan;50(1):63-68.
doi: 10.1055/s-0043-120666. Epub 2017 Nov 13.

Feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope for the detection of colorectal lesions

Maxime E S Bronzwaer  1 , Evelien Dekker  1   2 , Vincens Weingart  3 , Stefan Groth  4 , Mathieu Pioche  5 , Jérôme Rivory  5 , Torsten Beyna  6 , Horst Neuhaus  6 , Thierry Ponchon  5 , Hans Allescher  3 , Paul Fockens  1   2 , Thomas Rösch  4
Affiliations
Clinical Trial

Feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope for the detection of colorectal lesions

Maxime E S Bronzwaer et al. Endoscopy. 2018 Jan.

Abstract

Background and study aims: The adenoma detection rate (ADR) of conventional colonoscopy can still be improved. We conducted a prospective multicenter cohort study to assess the feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope, which offers a 235° view obtained from a forward-viewing and two lateral backward-viewing lenses incorporated into one image.

Patients and methods: The study was performed between November 2015 and June 2016. EWAVE colonoscopy was performed in patients with an increased risk of colorectal cancer by experienced and EWAVE-trained endoscopists (≥ 500 colonoscopies, ≥ 10 with the EWAVE system).

Results: A total of 193 patients underwent EWAVE colonoscopy. The cecal intubation rate was 97.4 %. EWAVE colonoscopy had a polyp detection rate (PDR) of 61.1 % (118 /193), ADR of 39.9 % (77 /193), and advanced ADR of 13.5 % (26 /193). No adverse events occurred.

Conclusions: EWAVE colonoscopy is feasible and safe. The ADR appears comparable to those achieved with conventional colonoscopes in similar patient populations. To further elucidate the additional benefits of wide-angle-view colonoscopes, randomized trials would be required.

PubMed Disclaimer

Conflict of interest statement

Competing interests: Olympus provided the endoscopes and systems, paid a fee per patient to the hospitals for the documentation work, and covered the IRB/insurance costs. There was no personal funding for this study.

Associated data