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Observational Study
. 2017 Nov;96(45):e8395.
doi: 10.1097/MD.0000000000008395.

Effect of different surgical type of coronary artery bypass grafting on kidney injury: A propensity score analysis

Ming-Jen Chan  1 , Cheng-Chia Lee, Shao-Wei Chen, Feng-Chun Tsai, Pyng-Jing Lin, Pei-Chun Fan, Hsiang-Hao Hsu, Ming-Yang Chang, Yung-Chang Chen, Chih-Hsiang Chang
Affiliations
Observational Study

Effect of different surgical type of coronary artery bypass grafting on kidney injury: A propensity score analysis

Ming-Jen Chan et al. Medicine (Baltimore). 2017 Nov.

Erratum in

Abstract

Acute kidney injury (AKI) after coronary artery bypass grafting (CABG) is associated with a less favorable outcome. Off-pump surgery results in lower kidney dysfunction than conventional on-pump arrest surgery. On-pump arrest surgery results in a lower revascularization rate compared with off-pump surgery. On-pump beating heart (OPBH) CABG combines the advantages of beating heart surgery and cardiopulmonary bypass. This study compared the renal outcomes of 3 cardiac surgical methods. From January 2010 to December 2012, 373 patients who underwent on-pump CABG were enrolled. Propensity analysis was performed to compare the postoperative outcomes of postoperative AKI, renal replacement therapy (RRT), intensive care unit (ICU) stay, mortality, and extubating time. In total, 98 patients received conventional on-pump surgery, 160 received OPBH surgery, and 115 received off-pump surgery. The Society of Thoracic Surgeons scores of these 3 groups were 6.1 ± 13.6, 7.4 ± 13.6, and 5.6 ± 10.9, respectively. Propensity analysis revealed lower AKI incidence in the off-pump group than in the on-pump surgery group. No substantial differences were observed in mortality, RRT, and the ICU stay between the off-pump and OPBH surgery groups. Among the 3 surgical methods, off-pump surgery results in lower AKI incidence. The short-term outcome, including kidney function, of OPBH surgery is similar to that of the off-pump group. Therefore, OPBH surgery is a considerable choice for patients with a high surgical risk.

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Conflict of interest statement

Conflicts of interest: Dr C-H Chang was supported by the Ministry of Science and Technology (MOST 103–2314-B-182A-018-MY3).

Figures

Figure 1
Figure 1
Comparison of incidence of categorical outcome among surgical methods. The combined odds ratio was estimated using the quintile of propensity score as a stratum variable in the logistic regression model.
Figure 2
Figure 2
Comparison of continuous outcome among surgical methods. The combined regression coefficient was estimated using the linear mixed-effect model using the quintile of propensity score as a clustered variable.
See this image and copyright information in PMC

References

    1. Rosner MH, Okusa MD. Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol 2006;1:19–32. - PubMed
    1. Gallagher S, Jones DA, Lovell MJ, et al. The impact of acute kidney injury on midterm outcomes after coronary artery bypass graft surgery: a matched propensity score analysis. J Thorac Cardiovasc Surg 2014;147:989–95. - PubMed
    1. Ryden L, Ahnve S, Bell M, et al. Acute kidney injury after coronary artery bypass grafting and long-term risk of myocardial infarction and death. Int J Cardiol 2014;172:190–5. - PubMed
    1. Reents W, Hilker M, Borgermann J, et al. Acute kidney injury after on-pump or off-pump coronary artery bypass grafting in elderly patients. Ann Thorac Surg 2014;98:9–14. [discussion 14-15]. - PubMed
    1. Chen SW, Chang CH, Fan PC, et al. Comparison of contemporary preoperative risk models at predicting acute kidney injury after isolated coronary artery bypass grafting: a retrospective cohort study. BMJ Open 2016;6:e010176. - PMC - PubMed

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