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Review
. 2018 Feb;22(1):191-205.
doi: 10.1007/s11030-017-9796-x. Epub 2017 Nov 14.

Recent trends in ring opening of epoxides with sulfur nucleophiles

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Review

Recent trends in ring opening of epoxides with sulfur nucleophiles

Sajjad Ahmad et al. Mol Divers. 2018 Feb.

Abstract

Thiolysis of epoxides offers an efficient and simple synthetic approach to access [Formula: see text]-hydroxy sulfides which are valuable scaffold in the synthesis of various important molecules in medicinal chemistry. This review article presents a recent compilation of the synthetic approaches developed after 2000 for the thiolysis of epoxides.

Keywords: -Hydroxy sulfides; Epoxides; Organosulfur compounds; Thiols; Thiolysis.

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References

    1. Chem Rev. 2016 Dec 28;116(24):15167-15197 - PubMed
    1. J Nat Prod. 2006 Oct;69(10 ):1384-8 - PubMed
    1. Langmuir. 2006 Apr 11;22(8):3494-6 - PubMed
    1. Chem Rev. 2015 May 13;115(9):3564-614 - PubMed
    1. J Med Chem. 1987 Sep;30(9):1609-16 - PubMed

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