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. 2018 Jan 4;46(D1):D41-D47.
doi: 10.1093/nar/gkx1094.

GenBank

Dennis A Benson  1 , Mark Cavanaugh  1 , Karen Clark  1 , Ilene Karsch-Mizrachi  1 , James Ostell  1 , Kim D Pruitt  1 , Eric W Sayers  1
Affiliations

GenBank

Dennis A Benson et al. Nucleic Acids Res. .

Abstract

GenBank® (www.ncbi.nlm.nih.gov/genbank/) is a comprehensive database that contains publicly available nucleotide sequences for 400 000 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole genome shotgun and environmental sampling projects. Most submissions are made using BankIt, the National Center for Biotechnology Information (NCBI) Submission Portal, or the tool tbl2asn. GenBank staff assign accession numbers upon data receipt. Daily data exchange with the European Nucleotide Archive and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the NCBI Nucleotide database, which links to related information such as taxonomy, genomes, protein sequences and structures, and biomedical journal literature in PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. Recent updates include changes to sequence identifiers, submission wizards for 16S and Influenza sequences, and an Identical Protein Groups resource.

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Figures

Figure 1.
Figure 1.
Size in base pairs of the five GenBank divisions with the highest annual growth rates in 2017. The growth of GenBank as a whole is also shown as ‘TOTAL’.
See this image and copyright information in PMC

References

    1. Benson D.A., Cavanaugh M., Clark K., Karsch-Mizrachi I., Lipman D.J., Ostell J., Sayers E.W.. GenBank. Nucleic Acids Res. 2017; 45:D37–D42. - PMC - PubMed
    1. Toribio A.L., Alako B., Amid C., Cerdeno-Tarraga A., Clarke L., Cleland I., Fairley S., Gibson R., Goodgame N., Ten Hoopen P. et al. . European Nucleotide Archive in 2016. Nucleic Acids Res. 2017; 45:D32–D36. - PMC - PubMed
    1. Mashima J., Kodama Y., Fujisawa T., Katayama T., Okuda Y., Kaminuma E., Ogasawara O., Okubo K., Nakamura Y., Takagi T.. DNA Data Bank of Japan. Nucleic Acids Res. 2017; 45:D25–D31. - PMC - PubMed
    1. Cochrane G., Karsch-Mizrachi I., Takagi T. International Nucleotide Sequence Database, C. . The International Nucleotide Sequence Database Collaboration. Nucleic Acids Res. 2016; 44:D48–D50. - PMC - PubMed
    1. NCBI Resource Coordinators Database Resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2017; 45:D12–D17. - PMC - PubMed

Publication types