Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jan 4;46(D1):D36-D40.
doi: 10.1093/nar/gkx1125.

The European Nucleotide Archive in 2017

Nicole Silvester  1 , Blaise Alako  1 , Clara Amid  1 , Ana Cerdeño-Tarrága  1 , Laura Clarke  1 , Iain Cleland  1 , Peter W Harrison  1 , Suran Jayathilaka  1 , Simon Kay  1 , Thomas Keane  1 , Rasko Leinonen  1 , Xin Liu  1 , Josué Martínez-Villacorta  1 , Manuela Menchi  1 , Kethi Reddy  1 , Nima Pakseresht  1 , Jeena Rajan  1 , Marc Rossello  1 , Dmitriy Smirnov  1 , Ana L Toribio  1 , Daniel Vaughan  1 , Vadim Zalunin  1 , Guy Cochrane  1
Affiliations

The European Nucleotide Archive in 2017

Nicole Silvester et al. Nucleic Acids Res. .

Abstract

For 35 years the European Nucleotide Archive (ENA; https://www.ebi.ac.uk/ena) has been responsible for making the world's public sequencing data available to the scientific community. Advances in sequencing technology have driven exponential growth in the volume of data to be processed and stored and a substantial broadening of the user community. Here, we outline ENA services and content in 2017 and provide insight into a selection of current key areas of development in ENA driven by challenges arising from the above growth.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Number of WGS sets accessioned each month at ENA.
Figure 2.
Figure 2.
Total number of public sequences contained in each release of ENA’s assembled and annotated sequence database from June 1982 to June 2017. From June 2004, when WGS sequences were first included in the release, the WGS proportion is also illustrated.
Figure 3.
Figure 3.
Recent growth in the Sequence Version Archive database. This is given as the compressed data size.
See this image and copyright information in PMC

References

    1. Smith L.M., Sanders J.Z., Kaiser R.J., Hughes P., Dodd C., Connell C.R., Heiner C., Kent S.B., Hood L.E.. Fluorescence detection in automated DNA sequence analysis. Nature. 1986; 321:674–679. - PubMed
    1. Ansorge W., Sproat B., Stegemann J., Schwager C., Zenke M.. Automated DNA sequencing: ultrasensitive detection of fluorescent bands during electrophoresis. Nucleic Acids Res. 1987; 15:4593–4602. - PMC - PubMed
    1. Hunkapiller T., Kaiser R.J., Koop B.F., Hood L.. Large-scale and automated DNA sequence determination. Science. 1991; 254:59–67. - PubMed
    1. Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., Dewar K., Doyle M., FitzHugh W. et al. . Initial sequencing and analysis of the human genome. Nature. 2001; 409:860–921. - PubMed
    1. Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A. et al. . The sequence of the human genome. Science. 2001; 291:1304–1351. - PubMed

Publication types

LinkOut - more resources