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. 2017 Oct-Dec;32(4):380-382.
doi: 10.4103/ijnm.IJNM_93_17.

Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging in the Diagnosis of Cardiac Paraganglioma

Nicholas Bhojwani  1 , Jennifer Huang  2 , Vasant Garg  3 , Michael Yang  4 , Guilherme H Oliveira  5 , Prabhakar Rajiah  3
Affiliations

Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging in the Diagnosis of Cardiac Paraganglioma

Nicholas Bhojwani et al. Indian J Nucl Med. 2017 Oct-Dec.

Abstract

Cardiac paragangliomas are rare tumors of neural crest origin, most frequently seen in the left atrium. There are mixed opinions regarding the most appropriate imaging study for diagnosis and evaluation. We describe the novel utility of 18-F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in the case of a 42-year-old male with cardiac paraganglioma.

Keywords: 18F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging; cardiac paraganglioma; neuroendocrine tumor.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Axial intravenous contrast-enhanced computed tomography image shows an intensely enhancing well-defined mass (arrow) between the left superior pulmonary vein and the pulmonary artery and abutting the left anterior descending artery
Figure 2
Figure 2
Hybrid 18F-Fluorodeoxyglucose positron emission tomography/magnetic resonance (Philips Ingenuity TF PET/MR Philips Healthcare, Andover, MA, USA) was performed. (a) Vertical long axis T2-weighted magnetic resonance image shows a hyperintense epicardial mass measuring 3 cm × 1.8 cm abutting the left anterior descending artery. (b) Axial postcontrast T1 fat suppressed magnetic resonance imaging shows intense contrast enhancement of the mass
Figure 3
Figure 3
Axial (a) and coronal (b) hybrid 18F-Fluorodeoxyglucose positron emission tomography/magnetic resonance images of the same patient show the mass to be intensely hypermetabolic with standard uptake value of 16. No other hypermetabolic mass is seen to suggest metastatic disease
Figure 4
Figure 4
Gross surgical specimen of faint blue and tan-red muscular soft tissue with attached tan-yellow soft fatty tissue measuring 2.9 cm × 2.8 cm × 1.9 cm
Figure 5
Figure 5
Histopathological image at 100× magnification (a) a tumor with classic Zellballen cell nests with rich vascular network and intervening fibrous bands. The same histopathological image at 400× (b) moderate nuclear atypia with “salt-and-pepper” chromatin pattern. This was consistent with paraganglioma
See this image and copyright information in PMC

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