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. 2017 Oct;9(5):402-408.
doi: 10.4047/jap.2017.9.5.402. Epub 2017 Oct 16.

Adherence of Candida to complete denture surfaces in vitro: A comparison of conventional and CAD/CAM complete dentures

Afnan F Al-Fouzan  1 , Lamya A Al-Mejrad  1 , Ahmed M Albarrag  2
Affiliations

Adherence of Candida to complete denture surfaces in vitro: A comparison of conventional and CAD/CAM complete dentures

Afnan F Al-Fouzan et al. J Adv Prosthodont. 2017 Oct.

Abstract

Purpose: The goal of this study was to compare the adhesion of Candida albicans to the surfaces of CAD/CAM and conventionally fabricated complete denture bases.

Materials and methods: Twenty discs of acrylic resin poly (methyl methacrylate) were fabricated with CAD/CAM and conventional procedures (heat-polymerized acrylic resin). The specimens were divided into two groups: 10 discs were fabricated using the CAD/CAM procedure (Wieland Digital Denture Ivoclar Vivadent), and 10 discs were fabricated using a conventional flasking and pressure-pack technique. Candida colonization was performed on all the specimens using four Candida albicans isolates. The difference in Candida albicans adhesion on the discs was evaluated. The number of adherent yeast cells was calculated by the colony-forming units (CFU) and by Fluorescence microscopy.

Results: There was a significant difference in the adhesion of Candida albicans to the complete denture bases created with CAD/CAM and the adhesion to those created with the conventional procedure. The CAD/CAM denture bases exhibited less adhesion of Candida albicans than did the denture bases created with the conventional procedure (P<.05).

Conclusion: The CAD/CAM procedure for fabricating complete dentures showed promising potential for reducing the adherence of Candida to the denture base surface. Clinical Implications. Complete dentures made with the CAD/CAM procedure might decrease the incidence of denture stomatitis compared with conventional dentures.

Keywords: Adhesion; CAD/CAM; Candida; Complete denture; Edentulous; Roughness.

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Figures

Fig. 1
Fig. 1. Surface roughness of the CAD/CAM complete denture base.
Fig. 2
Fig. 2. Surface roughness of the conventional complete denture base.
Fig. 3
Fig. 3. Candida cells adhered to the conventional discs (stained with acridine orange).
Fig. 4
Fig. 4. Candida cells adhered to the CAD/CAM discs (stained with acridine orange).
See this image and copyright information in PMC

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