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Case Reports
. 2017 Nov;96(46):e8756.
doi: 10.1097/MD.0000000000008756.

Endocarditis due to Abiotrophia defectiva, a biofilm-related infection associated with the presence of fixed braces: A case report

Victoria Birlutiu  1 , Rares Mircea Birlutiu
Affiliations
Case Reports

Endocarditis due to Abiotrophia defectiva, a biofilm-related infection associated with the presence of fixed braces: A case report

Victoria Birlutiu et al. Medicine (Baltimore). 2017 Nov.

Abstract

Rationale: Endocarditis with Abiotrophia defectiva represents 4.3% to 6% of all streptococcal endocarditis. The article presents diagnosis issues and the complexity of the treatment.

Patient concerns: We present the case of a female white patient, aged 26 years, who developed infectious endocarditis caused by A defectiva, in the last trimester of pregnancy, a biofilm-related infection associated with the presence of fixed braces.

Diagnoses: The diagnosis of infectious endocarditis was confirmed by the cardiac ultrasound examination that revealed a voluminous vegetation on the mitral valve, and acute mitral regurgitation caused by chordae tendinae rupture, and also by isolating Abiotrophia defectiva from two positive blood cultures.

Interventions: The decision to undergo surgical intervention was taken, and a mitral valve replacement was performed. Surgical intervention that was associated with board-spectrum antibiotic therapy.

Outcomes: A defectiva, remains a rare cause of infective endocarditis, with a reserved prognosis that is motivated by the extensive valvular lesions and the risk of embolism.

Lessons: The use of antibiotics administered in association, in the management of infective endocarditis, is mandatory.

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Conflict of interest statement

The authors report no conflicts of interest.

References

    1. Kawamura Y, Hou X, Sultana F, et al. Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adiacens comb. nov. and Abiotrophia defectiva comb. nov., respectively. Int J Syst Bacteriol 1995;45:798–803. - PubMed
    1. Roggenkamp A, Abele-Horn M, Trebesius KH, et al. Abiotrophia elegans sp. nov., a possible pathogen in patients with culture-negative endocarditis. J Clin Microbiol 1998;36:100–4. - PMC - PubMed
    1. Lawson PA, Foster G, Falsen E, et al. Abiotrophia balaenopterae sp. nov., isolated from the minke whale (Balaenoptera acutorostrata). Int J Syst Bacteriol 1999;49(part 2):503–6. - PubMed
    1. Kanamoto T, Sato S, Inoue M. Genetic heterogeneities and phenotypic characteristics of strains of the genus Abiotrophia and proposal of Abiotrophia para-adiacens sp. nov. J Clin Microbiol 2000;38:492–8. - PMC - PubMed
    1. Flemming HC, Wingender J, Griebe T, et al. Physico-Chemical Properties of Biofilms. In Evans LV, Biofilms: Recent Advances in their Study and Control. Amsterdam, The Netherlands: CRC Press; 2000:20.

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