Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Nov 16;171(5):992-993.
doi: 10.1016/j.cell.2017.11.004.

Risky Business: The Circuits that Impact Stress-Induced Decision-Making

Amy F T Arnsten  1 , Daeyeol Lee  2 , Christopher Pittenger  3
Affiliations
Free article
Comment

Risky Business: The Circuits that Impact Stress-Induced Decision-Making

Amy F T Arnsten et al. Cell. .
Free article

Abstract

How does stress promote risky decision-making? Friedman et al. find that stress disrupts inhibition of striatal circuits by prefrontal cortex, rendering animals insensitive to potential losses. This may help explain how stress contributes to substance abuse and how it can disinhibit automatic behaviors, such as tics in Tourette syndrome.

PubMed Disclaimer

Comment on

LinkOut - more resources