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Review
. 2017 Nov 17;43(1):103.
doi: 10.1186/s13052-017-0421-5.

Cardiac arrest in a toddler treated with propranolol for infantile Hemangioma: a case report

Alvise Tosoni  1 , Mario Cutrone  2 , Maurizio Dalle Carbonare  3 , Andrea Pettenazzo  4 , Giorgio Perilongo  5 , Stefano Sartori  5
Affiliations
Review

Cardiac arrest in a toddler treated with propranolol for infantile Hemangioma: a case report

Alvise Tosoni et al. Ital J Pediatr. .

Abstract

Background: Propranolol has become the first-line treatment for complicated Infantile Hemangioma (IH), showing so far a good risk-benefit profile.

Case presentation: We report the case of a toddler, on propranolol, who suffered cardiac arrest during an acute viral infection. She had a neurally-mediated syncope that progressed to asystole, probably because of concurrent factors as dehydration, beta-blocking and probably individual susceptibility to vaso-vagal phenomena. In fact a significant history of breath-holding spells was consistent with vagal hyperactivity.

Conclusions: The number of patients treated with propranolol for IHs will increase and sharing experience will help to better define the safety profile of this drug.

Keywords: Adrenergic beta-blockers; Asystole; Child.

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Conflict of interest statement

Ethics approval and consent to participate

Not applicable according to our Institutional Research Ethic Boards.

Consent for publication

Consent to publication was obtained from parents.

Competing interests

The authors declare that they have no competing interests.

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Figures

Fig. 1
Fig. 1
a before starting medical treatment with propranolol. b 8-day follow-up. c 37-day follow-up
See this image and copyright information in PMC

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