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. 2018 Feb;41(2):293-302.
doi: 10.2337/dc17-1259. Epub 2017 Nov 17.

Declining Rates of Hospitalization for Selected Cardiovascular Disease Conditions Among Adults Aged ≥35 Years With Diagnosed Diabetes, U.S., 1998-2014

Nilka Ríos Burrows  1 , YanFeng Li  2 , Edward W Gregg  2 , Linda S Geiss  2
Affiliations

Declining Rates of Hospitalization for Selected Cardiovascular Disease Conditions Among Adults Aged ≥35 Years With Diagnosed Diabetes, U.S., 1998-2014

Nilka Ríos Burrows et al. Diabetes Care. 2018 Feb.

Abstract

Objective: Reductions in heart attack and stroke hospitalizations are well documented in the U.S. population with diabetes. We extended trend analyses to other cardiovascular disease (CVD) conditions, including stroke by type, and used four additional years of data.

Research design and methods: Using 1998-2014 National (Nationwide) Inpatient Sample (NIS) data, we estimated the number of discharges having acute coronary syndrome (ACS) (ICD-9 codes 410-411), cardiac dysrhythmia (427), heart failure (428), hemorrhagic stroke (430-432), or ischemic stroke (433.x1, 434, and 436) as first-listed diagnosis and diabetes (250) as secondary diagnosis. Hospitalization rates for adults aged ≥35 years were calculated using estimates from the population with and the population without diabetes from the National Health Interview Survey (NHIS) and age-adjusted to the 2000 U.S. standard population. Joinpoint regression was used to analyze trends and calculate an average annual percentage change (AAPC) with 95% confidence limits (CLs).

Results: From 1998 to 2014, in the population with diabetes, age-adjusted hospitalization rates declined significantly for ACS (AAPC -4.6% per year [95% CL -5.3, -3.8]), cardiac dysrhythmia (-0.7% [-1.1, -0.2]), heart failure (-3.6% [-4.6, -2.7]), hemorrhagic stroke (-1.1% [-1.4, -0.7]), and ischemic stroke (-2.9% [-3.9, -1.8]). In the population without diabetes, rates also declined significantly for these conditions, with the exception of dysrhythmia. By 2014, rates in the population with diabetes population remained two to four times as high as those for the population without diabetes, with the largest difference in heart failure rates.

Conclusions: CVD hospitalization rates declined significantly in both the population with diabetes and the population without diabetes. This may be due to several factors, including new or more aggressive treatments and reductions in CVD risk factors and CVD incidence.

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Conflict of interest statement

Duality of Interest. No potential conflicts of interest relevant to this article were reported.

Figures

Figure 1
Figure 1
Age-adjusted hospitalization rates for selected CVD conditions among people aged ≥35 years with diagnosed diabetes, by sex (U.S., 1998–2014). Per 1,000 population with diabetes and age-adjusted based on the 2000 U.S. standard population. Symbols represent observed hospitalization rates, and lines represent modeled trends using Joinpoint regression. ■, heart failure; □, ACS; △, ischemic stroke; ●, cardiac dysrhythmia; ◆, hemorrhagic stroke.
Figure 2
Figure 2
Age-adjusted hospitalization rates for selected CVD conditions among people aged ≥35 years with diagnosed diabetes, by race/ethnicity (U.S., 1998–2014). Per 1,000 population with diabetes and age-adjusted based on the 2000 U.S. standard population. Symbols represent observed rates, and lines represent modeled trends. ■, heart failure; □, ACS; △, ischemic stroke; ●, cardiac dysrhythmia; ◆, hemorrhagic stroke.
See this image and copyright information in PMC

Comment in

References

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