Comment
doi: 10.1016/j.kint.2017.07.012.
CKD stage V in AL amyloidosis: is it too late to treat? Maybe not
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- PMID: 29153137
- DOI: 10.1016/j.kint.2017.07.012
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CKD stage V in AL amyloidosis: is it too late to treat? Maybe not
Kidney Int.
2017 Dec.
Free article
Abstract
Ig light chain amyloidosis is a protein misfolding disease capable of causing multiorgan failure. Organ failure can be stopped by reducing the production of Ig light chain. The current study by Rezk et al. found that even patients with advanced chronic kidney disease can benefit if the serum free light chain can be substantially reduced within the first 3 months. This, if confirmed, can have a huge impact in the management of these patients.
Copyright © 2017 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
Comment on
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Prolonged renal survival in light chain amyloidosis: speed and magnitude of light chain reduction is the crucial factor.Kidney Int. 2017 Dec;92(6):1476-1483. doi: 10.1016/j.kint.2017.05.004. Epub 2017 Jul 18. Kidney Int. 2017. PMID: 28729034
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