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. 1989 Mar;63(3):1428-30.
doi: 10.1128/JVI.63.3.1428-1430.1989.

Self-ligating RNA sequences on the antigenome of human hepatitis delta virus

L Sharmeen  1 , M Y Kuo, J Taylor
Affiliations

Self-ligating RNA sequences on the antigenome of human hepatitis delta virus

L Sharmeen et al. J Virol. 1989 Mar.

Abstract

A 179-base fragment of RNA from the 1,679-base antigenome of hepatitis delta virus can not only self-cleave but, when the ends of the resultant fragments are brought into apposition by base pairing to another RNA, also self-ligate. Thus, processing events needed for genome replication in vivo may be strictly RNA mediated.

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