Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Dec;23(13):S53-S56.
doi: 10.3201/eid2313.170366.

Capacity Development through the US President's Malaria Initiative-Supported Antimalarial Resistance Monitoring in Africa Network

Eric S Halsey, Meera Venkatesan, Mateusz M Plucinski, Eldin Talundzic, Naomi W Lucchi, Zhiyong Zhou, Celine I Mandara, Hawela Moonga, Busiku Hamainza, Abdoul Habib Beavogui, Simon Kariuki, Aaron M Samuels, Laura C Steinhardt, Don P Mathanga, Julie Gutman, Yves Eric Denon, Aline Uwimana, Ashenafi Assefa, Jimee Hwang, Ya Ping Shi, Pedro Rafael Dimbu, Ousmane Koita, Deus S Ishengoma, Daouda Ndiaye, Venkatachalam Udhayakumar

Capacity Development through the US President's Malaria Initiative-Supported Antimalarial Resistance Monitoring in Africa Network

Eric S Halsey et al. Emerg Infect Dis. 2017 Dec.

Abstract

Antimalarial drug resistance is an evolving global health security threat to malaria control. Early detection of Plasmodium falciparum resistance through therapeutic efficacy studies and associated genetic analyses may facilitate timely implementation of intervention strategies. The US President's Malaria Initiative-supported Antimalarial Resistance Monitoring in Africa Network has assisted numerous laboratories in partner countries in acquiring the knowledge and capability to independently monitor for molecular markers of antimalarial drug resistance.

Keywords: Africa; antimalarial drugs; antimicrobial resistance; artemisinins; capacity building; genetic markers; global health security; malaria; parasites; tropical medicine.

PubMed Disclaimer

Figures

Figure
Figure
US President’s Malaria Initiative (PMI)–supported therapeutic efficacy study (TES) sites, where samples were collected to test for molecular markers of antimalarial drug resistance, 2015–2017.
See this image and copyright information in PMC

References

    1. World Health Organization. World malaria report, 2016.[cited 2017 Jul 21]. http://www.who.int/malaria/media/world-malaria-report-2016/en/
    1. Guidelines for the treatment of malaria. 3rd ed. Geneva: World Health Organization; 2015. - PubMed
    1. Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, et al. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature. 2015;526:207–11. 10.1038/nature15535 - DOI - PMC - PubMed
    1. Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, et al. Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2009;361:455–67. 10.1056/NEJMoa0808859 - DOI - PMC - PubMed
    1. Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al.; Tracking Resistance to Artemisinin Collaboration (TRAC). Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411–23. 10.1056/NEJMoa1314981 - DOI - PMC - PubMed

Publication types

LinkOut - more resources