Strengthening Global Surveillance for Antimicrobial Drug-Resistant Neisseria gonorrhoeae through the Enhanced Gonococcal Antimicrobial Surveillance Program

Abstract

Monitoring trends in antimicrobial drug-resistant Neisseria gonorrhoeae is a critical public health and global health security activity because the number of antimicrobial drugs available to treat gonorrhea effectively is rapidly diminishing. Current global surveillance methods for antimicrobial drug-resistant N. gonorrhoeae have many limitations, especially in countries with the greatest burden of disease. The Enhanced Gonococcal Antimicrobial Surveillance Program is a collaboration between the World Health Organization and the Centers for Disease Control and Prevention. The program aims to monitor trends in antimicrobial drug susceptibilities in N. gonorrhoeae by using standardized sampling and laboratory protocols; to improve the quality, comparability, and timeliness of gonococcal antimicrobial drug resistance data across multiple countries; and to assess resistance patterns in key populations at highest risk for antimicrobial drug-resistant gonorrhea so country-specific treatment guidelines can be informed.

Keywords: AGSP; AMR; CARB; EGASP; Euro-GASP; GISP; GLASS; GRASP; Neisseria gonorrhoeae; antibiotic; antimicrobial; antimicrobial resistance; azithromycin; bacteria; ceftriaxone; ciprofloxacin; global health security; gonococcal; gonorrhea; penicillin; quinolones; sexually transmitted disease; sexually transmitted infections; surveillance; tetracycline; urethral discharge.