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Editorial
. 2017 Sep 28;8(49):84610-84611.
doi: 10.18632/oncotarget.21295. eCollection 2017 Oct 17.

VEGFR3 as a novel modulator for PAH

Heon-Woo Lee  1 , Suk-Won Jin  1
Affiliations
Editorial

VEGFR3 as a novel modulator for PAH

Heon-Woo Lee et al. Oncotarget. .
No abstract available

Keywords: BMPR2; VEGFR3; pulmonary hypertension; signaling.

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Figures

Figure 1
Figure 1. Interaction between BMPR2 and VEGFR3 is critical for the ligand induced endocytosis of BMP receptors in endothelial cells
BMPR2 is located at the endothelial cell surface membrane in the resting states. Upon ligand binding, BMPR2 may recruit VEGFR3 and undergoes Clathrin-mediated endocytosis to induce downstream signaling cascades such as phosphorylation of R-SMADs (SMAD1 and SMAD5).
See this image and copyright information in PMC

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