doi: 10.1080/10286020.2017.1403421.
Epub 2017 Nov 20.
Two new saponins from the leaves of Panax notoginseng
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- PMID: 29156976
- DOI: 10.1080/10286020.2017.1403421
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Two new saponins from the leaves of Panax notoginseng
J Asian Nat Prod Res.
2018 Apr.
Abstract
Two new saponins, notoginsenosides Ng1 (1) and Ng2 (2), together with seven known compounds (3-9), were isolated from the leaves of Panax notoginseng. Their structures were elucidated by UV, IR, HRESIMS, and NMR experiments. Compounds 6 and 7 showed moderate cytotoxic activities against HCT-116, with IC50 values of 4.98 and 0.64 μmol/L, respectively.
Keywords: Araliaceae; Panax notoginseng; anticancer; saponins.
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