Susceptibility-Weighted Imaging and Magnetic Resonance Spectroscopy in Concussion

Abstract

Although susceptibility-weighted imaging (SWI) studies have suggested an increased number of microhemorrhages in concussion, most show no significant differences compared with controls. There have been mixed results on using SWI to predict neurologic outcomes. Drawbacks include inability to time microhemorrhages and difficulty in attributing them to the concussion. Magnetic resonance spectroscopy (MRS) in concussion can identify metabolic abnormalities, with many studies showing correlations with clinical outcome. Applications in individual patients are impeded by conflicting data and lack of consensus on an optimal protocol. Therefore, currently MRS has most utility in group-level comparisons designed to reveal the pathophysiology of concussion.

Keywords: Concussion; Magnetic resonance spectroscopy (MRS); Mild traumatic brain injury (mTBI); SWI; Susceptibility-weighted imaging.