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. 2017 Sep 23:21:9-11.
doi: 10.1016/j.nmni.2017.09.005. eCollection 2018 Jan.

First complete genome sequence of circulating dengue virus serotype 3 in Jeddah, Saudi Arabia

A M Hashem  1   2 , S S Sohrab  1 , S A El-Kafrawy  1 , S A El-Ela  1 , A M M Abd-Alla  3   4 , S A Farraj  1 , N A Othman  1 , A M Hassan  1 , M M El-Daly  1 , R N Charrel  1   5 , T A Madani  6 , E I Azhar  1   7
Affiliations

First complete genome sequence of circulating dengue virus serotype 3 in Jeddah, Saudi Arabia

A M Hashem et al. New Microbes New Infect. .

Abstract

Here we report the first full-length genome sequence of dengue virus serotype 3 (DENV-3) from a strain isolated from a patient in Jeddah, Saudi Arabia, in 2014. The genome consists of 10 635 bp and shows close similarity to circulating genotype III isolates from Singapore, suggesting possible importation, most probably during religious pilgrimages to Saudi Arabia.

Keywords: DENV; Dengue virus; Saudi Arabia; full genome; genotypes.

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Figures

Fig. 1
Fig. 1
Phylogenetic trees of dengue virus serotype 3 (DENV-3). (a) Phylogenetic tree based on full genome sequences of DENV-3. (b) Phylogenetic tree based on complete E gene sequences of DENV-3. Phylogenetic trees were constructed using maximum likelihood method based on best-fit model of nucleotide substitution and bootstrapping of 1000 replicates in MEGA6 software. DENV-3 from this study indicated by red box.
See this image and copyright information in PMC

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