Intestinal Flossing Keeps Pathogens at Bay
- PMID: 29161588
- DOI: 10.1016/j.devcel.2017.11.006
Intestinal Flossing Keeps Pathogens at Bay
Abstract
Intraepithelial lymphocytes (IELs) are tissue-resident immune cells that surveil the intestine and provide the first line of defense against pathogens. Reporting in Cell, van Konijnenburg et al. (2017) combine high-resolution microscopy and intersectional genetic tools to provide a detailed characterization of IEL dynamics in response to both commensal and pathogenic microorganisms.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection.Cell. 2017 Nov 2;171(4):783-794.e13. doi: 10.1016/j.cell.2017.08.046. Epub 2017 Sep 21. Cell. 2017. PMID: 28942917 Free PMC article.
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