Mitosis sans Mitosis: The Mitotic Oscillator in Differentiation
- PMID: 29161589
- DOI: 10.1016/j.devcel.2017.11.001
Mitosis sans Mitosis: The Mitotic Oscillator in Differentiation
Abstract
Differentiation and proliferation are usually considered to be antagonistic partners in development. However, in a recent issue of Science, Al Jord et al. (2017) show that key regulators of the mitotic cycle are redeployed in differentiating multiciliated cells to promote ciliogenesis without mitotic progression.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Centriole amplification by mother and daughter centrioles differs in multiciliated cells.Nature. 2014 Dec 4;516(7529):104-7. doi: 10.1038/nature13770. Epub 2014 Oct 12. Nature. 2014. PMID: 25307055
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