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Comment
. 2017 Dec 4;214(12):3469-3470.
doi: 10.1084/jem.20172031. Epub 2017 Nov 21.

The amazing brain drain

Affiliations
Comment

The amazing brain drain

Marie Blanchette et al. J Exp Med. .

Abstract

In this issue of JEM, Antila et al. (https://doi.org/10.1084/jem.20170391) demonstrate that central nervous system lymphatics develop in the mouse meninges during early postnatal periods and display remarkable plasticity in adult periods through manipulation of VEGF-C-VEGFR3 signaling.

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Figures

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Insight from Marie Blanchette and Richard Daneman

Comment on

  • Development and plasticity of meningeal lymphatic vessels.
    Antila S, Karaman S, Nurmi H, Airavaara M, Voutilainen MH, Mathivet T, Chilov D, Li Z, Koppinen T, Park JH, Fang S, Aspelund A, Saarma M, Eichmann A, Thomas JL, Alitalo K. Antila S, et al. J Exp Med. 2017 Dec 4;214(12):3645-3667. doi: 10.1084/jem.20170391. Epub 2017 Nov 15. J Exp Med. 2017. PMID: 29141865 Free PMC article.

References

    1. Absinta M., et al. eLife. 2017 doi: 10.7554/eLife.29738. - DOI - PubMed
    1. Antila S., et al. J. Exp. Med. 2017 doi: 10.1084/jem.20170391. - DOI - PubMed
    1. Asgari M., et al. Sci. Rep. 2016 doi: 10.1038/srep38635. - DOI - PMC - PubMed
    1. Aspelund A., et al. J. Exp. Med. 2015 doi: 10.1084/jem.20142290. - DOI - PubMed
    1. Barker C.F., and Billingham R.E.. 1977. Adv. Immunol. 25:1–54. - PubMed

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