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Case Reports
. 2017 Nov;76(11 Suppl 2):19-21.

Benign Granuloma Masquerading as Squamous Cell Carcinoma Due to a "Floater"

Phalgoon A Shah  1 , Madeleine P Prat  1 , David C Hostler  1
Affiliations
Case Reports

Benign Granuloma Masquerading as Squamous Cell Carcinoma Due to a "Floater"

Phalgoon A Shah et al. Hawaii J Med Public Health. 2017 Nov.

Abstract

Pathology specimen cross-contamination is a rare phenomenon in diagnostic pathology. Such "floaters" may result in delayed, missed or erroneous diagnoses. We describe the case of a patient with benign granuloma of the lung initially misdiagnosed as squamous cell carcinoma due to a "floater."

Keywords: granuloma; humans; pathology; surgical/standards.

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Conflict of interest statement

None of the authors identify a conflict of interest.

Figures

Figure 1
Figure 1
CT coronal cut, lung window, showing right upper lobe nodule
Figure 2
Figure 2
CT axial cut, body window, showing 4R lymph node
Figure 3
Figure 3
Fused PET CT, axial cut, showing 4R lymph node
Figure 4
Figure 4
TBNA of right paratracheal lymph node, H&E, 400x, demonstrating predominantly lymphocytes, with rare admixed epithelioid cells
Figure 5
Figure 5
TBNA of right paratracheal lymph node, CK5/6, 400x, demonstrating the rare epithelioid cells are reactive with CK5/6
Figure 6
Figure 6
Wedge resection of right upper lobe nodule; Gomori-methamine-silver stain; 600x; demonstrating numerous small (4–6 microns), mildly pleomorphic yeast forms with focal grooving and narrow based budding
See this image and copyright information in PMC

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